Cardiopulmonary resuscitation (CPR) is a life-saving intervention used when someone’s heart stops beating or when they stop breathing. While the core principles of CPR—chest compressions and airway support—remain consistent, the environment in which it’s delivered dramatically affects how it’s performed. Comparing CPR in an operating room (OR) versus in everyday situations highlights differences in training, equipment, timing, and outcomes across these two settings 1,1.


In the OR, CPR is typically performed by a highly trained surgical team with immediate access to advanced medical equipment. Patients in surgery are continuously monitored, which allows clinicians to recognize signs of cardiac arrest almost instantly. This means CPR can be initiated within seconds, often before the heart has completely stopped. Furthermore, defibrillators, ventilators, and medications are already on hand, allowing for a seamless response.


Because surgical teams are trained to work together in high-stakes situations, CPR in the OR is often more coordinated and precise. Each team member knows their role—whether it’s performing compressions, managing the airway, administering drugs, or documenting events. Sometimes, compressions must be modified depending on the surgical procedure in progress, such as open-chest compressions during cardiac surgery or minimizing movement during brain or spinal operations 2,3.


Outside the OR, CPR may be initiated by bystanders until emergency responders are able to take over. Bystanders may have limited or no training. Unlike in a hospital, recognition of cardiac arrest can be delayed, which critically affects outcomes. Equipment like automated external defibrillators (AEDs) may not be immediately available, especially in homes or rural areas. In these situations, while certain guidelines have been established to guide the CPR process, CPR quality and timing can vary significantly 4,5.


In the OR, patients are typically already intubated or have advanced airway support, making oxygen delivery more controlled, whereas layperson CPR in everyday settings usually focuses on hands-only compressions unless the rescuer is trained in rescue breathing. The disparity in airway control between the two settings can influence the success of resuscitation efforts 6,7.


Cardiac arrest in the OR generally tends to have better survival rates than out-of-hospital cardiac arrests due to the speed and effectiveness of intervention. In-hospital arrests benefit from continuous monitoring, immediate intervention, and access to advanced care. Out-of-hospital outcomes, on the other hand, depend heavily on how quickly CPR is started, whether an AED is used, and the time it takes for emergency medical services to arrive 8–11.


While CPR serves the same fundamental purpose regardless of location, its execution in the OR is more immediate, structured, and technologically supported than in everyday life. Understanding these differences highlights the importance of public CPR training and access to AEDs while also appreciating the critical expertise of surgical teams when a crisis strikes in the operating room.

References

  1. Cardiopulmonary resuscitation (CPR): First aid – Mayo Clinic. https://www.mayoclinic.org/first-aid/first-aid-cpr/basics/art-20056600.
  2. Hinkelbein, J. et al. Cardiac arrest in the perioperative period: a consensus guideline for identification, treatment, and prevention from the European Society of Anaesthesiology and Intensive Care and the European Society for Trauma and Emergency Surgery. Eur J Trauma Emerg Surg 49, 2031–2046 (2023). DOI: 10.1097/EJA.0000000000001813
  3. CPR in the OR. https://www.hopkinsmedicine.org/news/articles/2016/09/cpr-in-the-or.
  4. Goyal, A., Sciammarella, J. C., Cusick, A. S. & Patel, P. H. Cardiopulmonary Resuscitation. in StatPearls (StatPearls Publishing, Treasure Island (FL), 2025).
  5. CPR Steps | How to Perform CPR. Red Cross https://www.redcross.org/take-a-class/cpr/performing-cpr/cpr-steps.
  6. Kill, C., Manegold, R. K., Fistera, D. & Risse, J. Airway management and ventilation techniques in resuscitation during advanced life support: an update. Journal of Anesthesia, Analgesia and Critical Care 4, 58 (2024).
  7. Mohamed, B. A. Airway Management During Cardiopulmonary Resuscitation. Curr Anesthesiol Rep 12, 363–372 (2022). DOI: 10.1007/s40140-022-00527-z
  8. CPR Facts and Stats. cpr.heart.org https://cpr.heart.org/en/resources/cpr-facts-and-stats.
  9. Ebell, M. H., Becker, L. A., Barry, H. C. & Hagen, M. Survival After In-Hospital Cardiopulmonary Resuscitation. J Gen Intern Med 13, 805–816 (1998). DOI: 10.1046/j.1525-1497.1998.00244.x
  10. Cheema, M. A. et al. Duration of in-hospital cardiopulmonary resuscitation and its effect on survival. Indian Heart J 71, 314–319 (2019). DOI: 10.1016/j.ihj.2019.09.002
  11. York, S. P., BS (Pharm), MBA, PhD Professor of Pharmacy Administration College of Pharmacy &. Health Sciences, St John’s University Jamaica, New. Response to Cardiac Arrests in Community Settings. https://www.uspharmacist.com/article/response-to-cardiac-arrests-in-community-settings.